🧬 pLM4CPPs
Predict Cell-Penetrating Peptides using Protein Language Models. Input up to 1,000 peptide sequences.
Predict CPP Activity
0 / 1,000 sequences
Excel/CSV should have a column named "sequence". FASTA format is also supported.
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Model Selection
Choose a protein language model for embedding generation and prediction.
Available Models: ESM2-320, ESM2-480, ESM2-640
Some models require pre-trained .h5 files from the repository.
Some models require pre-trained .h5 files from the repository.
About the Models
ESM2-320: Best balance of speed and accuracy (89.6% ACC) ✓ AVAILABLE
ESM2-480: Medium speed, good accuracy (~90% ACC) ✓ AVAILABLE
ESM2-640: Medium speed, good accuracy (~90% ACC) ✓ AVAILABLE
Note: Other models require additional pre-trained files
Privacy:
All uploaded sequences are processed securely and deleted immediately after prediction.
All uploaded sequences are processed securely and deleted immediately after prediction.
What are CPPs?
Cell-Penetrating Peptides (CPPs) are short peptides (5-50 amino acids) capable of crossing cell membranes. They are valuable for:
- Drug delivery systems
- Gene therapy applications
- Intracellular targeting
- Therapeutic molecule transport
Reference: Kumar et al., J. Chem. Inf. Model. 2025